Treatment with Cyclophosphamide for steroid-resistant nephrotic syndrome in children.

نویسندگان

  • Florentina Cucer
  • Ingrith Miron
  • Robert Müller
  • Codruta Iliescu Halitchi
  • Doina Mihaila
چکیده

The management of patients with steroid-resistant nephrotic syndrome remains difficult. We repport our experience with Cyclophosphamide therapy, in an attempt to compare the results between an oral protocol and two i.v. protocols. The complete and sustained general remission rate was 43.1%, which confirms the efficacy of the treatment, especially for children with minimal change nephrotic syndrome. For the i.v. administration we recommend only 6 month of therapy, due to severe side-effects in longer courses.

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عنوان ژورنال:
  • Maedica

دوره 5 3  شماره 

صفحات  -

تاریخ انتشار 2010